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Seizures in Dogs, Understanding the causes, how to manage them.

Seizures in dogs, including German Shepherds, can be alarming for any pet owner to witness. Understanding the causes, how to manage them, and the science behind seizures is crucial for providing the best care for your furry friend.


Seizure Chart
Chart showing Symptoms od Seizures in dogs

Causes of Seizures in Dogs

Seizures in dogs can be attributed to various factors, each with its own underlying mechanisms.


Here are some common causes:


1. Idiopathic Epilepsy: Often seen in dogs between 6 months and 6 years of age, idiopathic epilepsy is believed to have a genetic component, especially in certain breeds. It's characterized by recurrent seizures with no identifiable cause.

Idiopathic Epilepsy results is Seizures
explaining what is Idiopathic Epilepsy

2. Structural Epilepsy: Caused by structural changes in the brain due to trauma, tumors, stroke, or inflammation. MRI scans and other diagnostics are used to identify these abnormalities.


3. Metabolic Disorders: Liver or kidney disease, electrolyte imbalances, and low blood sugar can all cause seizures by disrupting the normal metabolic processes in the body.




image about Focal Seizures
image about Focal Seizures

4. Toxic Ingestion: Exposure to toxins such as antifreeze, certain plants, or foods like chocolate and xylitol can induce seizures.


5. Infectious Diseases: Infections that affect the brain, such as canine distemper or bacterial meningitis, can lead to seizures.


Also, its important to acknowledge that parasite infections can indeed cause seizures in dogs, highlighting the importance of regular parasite control and prevention in canine health care.


Parasites, both internal and external, can affect a dog's nervous system directly or indirectly, leading to seizures among other health issues.


Here are some of the ways through which parasites might provoke seizures in dogs:


1. Neurocysticercosis: Caused by the larval stage of the Taenia solium tapeworm, this condition occurs when cysts form in the brain, leading to neurological symptoms, including seizures. This condition is more common in regions where these tapeworms are prevalent and can affect humans as well.


image of explanation of a results of possible brain damage from Seizures
can a dog get Brain Damage from Seizures

2. Toxoplasmosis: This infection, caused by the parasite Toxoplasma gondii, can lead to seizures when it affects the brain. Dogs can become infected by ingesting the oocysts directly from contaminated soil, water, or cat feces, or by eating infected prey.


3. Baylisascaris procyonis: This roundworm, which is commonly found in raccoons, can cause a severe neurological condition known as neural larva migraines if the larvae are ingested by dogs. The larvae can migrate to the dog's brain, causing inflammation and potentially seizures

.

4. Ehrlichiosis and Other Tick-Borne Diseases: While not caused by parasites directly invading the nervous system, diseases transmitted by ticks, such as Ehrlichiosis, can lead to neurological complications and seizures due to systemic illness and inflammation.


chart about Grand Mal Seizures
Grand Mal Seizures

Prevention and Treatment

Preventing parasite infections is key to reducing the risk of seizures and other health issues in dogs. Regular use of anti-parasitic medications, as recommended by your veterinarian, can help prevent infections from common parasites like fleas, ticks, and intestinal worms. Keeping your dog's living environment clean and avoiding exposure to potentially contaminated areas are also important preventive measures.


If a parasite infection is suspected to be the cause of seizures in a dog, a veterinarian will conduct diagnostic tests, such as blood tests, fecal examinations, and possibly imaging studies like MRI, to identify the type of parasite involved. Treatment will then be tailored to the specific parasite, which may include anti-parasitic medications, supportive care for seizures, and other symptomatic treatments.


It's crucial to consult a veterinarian if you suspect your dog has a parasite infection or if your dog experiences seizures. Early diagnosis and appropriate treatment can significantly improve the prognosis for dogs with parasite-induced seizures. Remember, maintaining a regular preventive care routine is the best strategy to protect your dog from parasites and their potentially serious health consequences.


Flea and Tick preventives and other drugs

Certain medications, including some tick and flea preventatives and other drugs, can potentially cause seizures in dogs, especially in those with a predisposition to neurological issues. This reaction, however, is relatively rare and typically involves specific circumstances or sensitivities.

Understanding the potential risks associated with certain medications can help dog owners make informed decisions about their pets' health care.


Tick and Flea Preventatives

Some tick and flea preventatives, particularly those that are older or use certain classes of chemicals, have been reported to cause adverse reactions in some dogs, including seizures.


These reactions are more common with products that contain pyrethroids (a type of chemical found in many insecticides), which are more toxic to cats and certain dog breeds with specific genetic sensitivities. It's important to note that the risk varies significantly depending on the type of preventative (topical, oral, or collar), the active ingredients, and the individual dog's health and history.


Other Drugs That Can Cause Seizures

- Ivermectin: Used in some heartworm preventatives, ivermectin can cause seizures in dogs that are sensitive to it, particularly breeds with the MDR1 gene mutation, such as Collies, Shetland Sheepdogs, and Australian Shepherds.


- Fluralaner and Isoxazoline Class: Some oral flea and tick preventatives belong to the isoxazoline class (e.g., Bravecto, Nexgard, Simparica) and have been associated with reports of seizures in dogs, though the risk is considered low and these products are generally safe for most dogs.


- Certain Antibiotics and Antifungals: Medications like metronidazole (an antibiotic) and fluconazole (an antifungal) have been known to cause neurological side effects, including seizures, particularly at high doses or in dogs with pre-existing liver function issues.


Recommendations for Dog Owners


1. Consultation with a Veterinarian: Always discuss the best tick, flea, and overall parasite prevention strategies with your veterinarian, considering your dog's specific health history, breed, and lifestyle.


2. Report Adverse Reactions: If you suspect that a medication has caused an adverse reaction in your dog, including seizures, contact your veterinarian immediately. Reporting these incidents can also help regulatory agencies monitor product safety.


3. Follow Dosage Instructions Carefully: Always use medications as prescribed and never use products intended for other animals on your dog. Incorrect dosages can increase the risk of adverse reactions.


4. Consider Your Dog’s Health and Genetic Background: Be aware of your dog's genetic predispositions and existing health conditions when choosing medications. For example, dogs with the MDR1 gene mutation should be given lower doses of ivermectin, if used at all.


While the potential for seizures or other adverse reactions from tick and flea preventatives or other medications can be concerning, it's essential to weigh these risks against the dangers of tick and flea infestations, which can lead to serious diseases like Lyme disease, ehrlichiosis, and others. A discussion with your veterinarian can help you navigate these choices and select the safest, most effective prevention strategies for your pet.




image explaining what to do when a dog gets seizures
what to do when a dog gets a seizure

Science Behind Seizures

Seizures are the result of excessive electrical discharge in the brain's neurons. This disruption in normal brain activity can lead to the characteristic signs of a seizure, which may include convulsions, salivation, loss of consciousness, and involuntary urination or defecation.


Managing Seizures


1. Stay Calm: During a seizure, it's important to remain calm and ensure your dog is in a safe place where they cannot hurt themselves.


2. Timing: Keep track of how long the seizure lasts. Seizures longer than 5 minutes (status epilepticus) require immediate veterinary attention.


3. Post-Seizure Care: Dogs are often disoriented or temporarily blind after a seizure. Provide a quiet, comfortable space for them to recover.


4. Veterinary Consultation: Always consult a veterinarian after your dog has a seizure, even if it's a first-time, brief event. They can help determine the cause and appropriate treatment.


5. Medication: For dogs diagnosed with epilepsy, antiepileptic drugs (AEDs) may be prescribed to control seizures. Regular follow-ups and blood tests are important to monitor the effectiveness and adjust dosages as needed.


Studies and Research

Research into canine epilepsy is ongoing, with studies focusing on genetic markers, medication efficacy, and long-term management strategies. Key studies include:


- The EpiGBS project, aiming to identify genetic biomarkers for epilepsy in dogs.


- Research by the Canine Epilepsy Project at the University of Missouri, which is looking into the genetic causes of epilepsy in dogs to better understand and treat the condition.


When dealing with seizures in German Shepherds or any breed, it's paramount to work closely with your veterinarian. They can provide a diagnosis, tailor treatment plans, and offer the best advice on managing your dog's condition. Remember, while internet resources can provide valuable information, they should never replace professional veterinary care.

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